Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease characterized by esophageal inflammation and dysfunction. EoE is a rare disorder that was first recognized as a disease in 1993. In Europe, around 16 out of 100,000 inhabitants suffer from EoE, although there are large geographic variations.

EoE negatively impacts the quality of life of patients and their families, and is a burden to the health care system. EUREOS provides relevant information about the disease, diagnostic procedure and therapeutic options for EoE patients.

EoE, or eosinophilic esophagitis, is an chronic inflammatory condition of the esophagus which is caused and maintained mainly by an allergic reaction to food. EoE is characterized by esophageal symptoms (including swallowing difficulty, food impaction, and heartburn, among others) and inflammation of the esophagus by eosinophils, a type of white blood cell.

First described about 2 decades ago, EoE represents today a very frequent cause of difficulty swallowing, food impaction, regurgitation, vomiting, and decreased appetite, mainly in young people. However, EoE may affect patients of all ages and genders, but it is more common in males. In fact, the chronic nature of EoE and associated functioning disturbances significantly impact the quality of life of adults and children who suffer from this disorder.

EoE patients usually have other associated allergic diseases, so the management of this disorder can be especially tricky.