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New Evidence-based guidelines on EoE: the pillars for clinical practice in 2017

Written by Alfredo J Lucendo | Saturday, October 28th, 2017

An international group of experts and researchers in EoE, including several members of EUREOS, has developed new evidence-based guidelines on this disease under the auspices of United European Gastroenterology. The document, which has been published in the UEG Journal in open-access format, provides an updated framework for an integrative management of children and adults with EoE, after the previous guides were judged outdated or obsolete.

To develop the guidelines, a group of 21 experts, including adult and pediatric gatroenterologists, pathologists, allergists, nutritionists, ENT specialists and epidemiologists, used the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system in order to comply with current standards of evidence assessment in formulation of recommendations. An extensive literature search was conducted up to August 2015 and periodically updated.

The guidelines include an updated concept of EoE, evaluated information on disease epidemiology, risk factors, associated conditions, and natural history of EoE in children and adults. Diagnostic conditions and criteria, the yield of diagnostic and disease monitoring procedures, and evidence-based statements and recommendation on the utility of the several treatment options for patients EoE are provided. Recommendations on how to choose and implement treatment and long-term management are provided based on expert opinion and best clinical practice.

The content of the Guides is endorsed by several Scientific Societies, including the United European Gastroenterology (UEG), The European Society of Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), the European Academy of Allergy and Clinical Immunology (EAACI), and the European Society of Eosinophilic Oesophagitis (EUREOS).

Full access to the text can be obtained for free in the webpage of the United European Gastroenterology Journal at:

http://journals.sagepub.com/doi/full/10.1177/2050640616689525