The budesonide-induced treatment response in EoE is mirrored by several blood and serum markers. The absolute blood eosinophil count correlates with the oesophageal eosinophil density.
A recent multicenter international study shows that most of EoE patients with response to PPI present a sustained histological remission while on low-dose PPI maintenance therapy
A meta-analysis of 16,846 EoE patients included in 18 studies found no significant variations in the seasonal distribution of either the diagnosis or clinical recrudescence of the disease throughout the year.
Patients diagnosed of PPI-REE may also show disease remission after dietary/topical steroid treatment, and some patients with EoE may achieve disease remission after PPI monotherapy